CLU and Lewy body dementia: Major isoform switching in excitatory neurons was also observed in other genes such as CLU, where control and PD expressed ENST00000316403.15 (blue) as the major isoform, while the major isoform in AD and DLB was ENST00000518050.1/ENST00000519472.5 (orange; Fig. 3C).