The main antiphospholipid antibodies (APA) are lupus anticoagulant, IgG/IgM anti-cardiolipin, and IgG/IgM anti–β2 glycoprotein I antibodies.2While anti-phosphatidylserine-prothrombin, phosphatidic acid, phosphatidyl-ethanolamine, phosphatidyl-glycerol, phosphatidyl-inositol, phosphatidylserine, and annexin V are related to APS and seem to play a role in clinical practice, they are not considered as part of its diagnostic criteria.3This syndrome may be primary, when isolated, or secondary, when associated with a concomitant systemic disease (most commonly systemic erythematous lupus, or SLE).3 This evidence concerns the gene CD40LG and systemic lupus erythematosus.