For instance, a study reported that implants with a-MMP-8 levels exceeding 15.3 ng/mL had a higher probability of peri-implantitis, underscoring the importance of MMP-8 as a biomarker.15In the present study, the recognition of a threshold of 24 ng/mL for aMMP-8 levels as the optimal cutoff for diagnosing peri-implantitis has significant implications for clinical practice. Here, MMP8 is linked to Peri-Implantitis.