HDGFL2 and malaria: On May 17, 2024, we conducted a PubMed search for original articles with no restrictions on language or time period, using the search terms “histidine-rich protein 2 OR Rapid diagnostic test” AND “malaria” AND “persistence OR dynamics.” We found one systematic review of 31 studies that modelled the mean duration of HRP2 RDT positivity to be 15 days (95% CI 5–32); no studies were from low transmission settings.