MT-CO1 and in situ carcinoma: To confirm that TACO1's role in promoting stemness and cisplatin resistance is mediated through the MTCO1/OXPHOS/mtROS axis, we transfected MTCO1 plasmids into TACO1 knockdown T24‐CIS cells and treated them with GYY4137 (a complex IV inhibitor[18]) or MitoTEMPO (a mitochondria‐targeted antioxidant) (Figure S5A, Supporting Information).