Next, we asked whether intermittent vibration could enhance sleep in AD animals, including Elav‐Gal4>UAS‐Aβ42 (Aβ42), Elav‐Gal4>UAS‐APP (APP) flies and 5XFAD mice, all of which exhibited sleep disorders as reported previously.[46, 47, 48, 49, 50] Aβ42 flies showed sleep fragmentation (increased in sleep bout number) without changes in sleep time. This evidence concerns the gene APP and sleep disorder.