Consistent with our findings in MM cells, the protein level of β‐catenin was also correlated with PNPO expression (Figure 3K), and the use of MSAB and Wnt3a reversed the effects of PNPO on β‐catenin protein levels and osteoclasts differentiation (Figures S2E–J, Supporting Information). Here, WNT3A is linked to Miyoshi myopathy.