To correlate immune infiltration against loss of tumor cells (a measure of local tumor control), we determined relationships between CD4 T-, CD8 T-, and NK cell populations and E-cadherin+ cells across all tumor sections (independent of treatment) and found a significant inverse correlation for both CD8 T- and NK cells (r2=−0.3, p=0.038 and r2=−0.33, p=0.026, respectively), but not CD4 T-cells (Figure 4B). The gene discussed is CD4; the disease is neoplasm.