NK-derived FLT3L correlated with increased cDC1 infiltration and improved overall survival and enhanced αPD1 treatment responses in melanoma (Barry et al., 2018), while intra-tumoral NK cells correlate with increased T-cell and dendritic cell infiltration and improved survival in neuroblastoma (Melaiu et al., 2020). The gene discussed is FLT3LG; the disease is melanoma.