CFTR and cystic fibrosis: Furthermore, the Arabic-speaking population in the Middle East has a high prevalence of CFTR gene mutation.26 In the management of lung infection resulting from P. aeruginosa, inhaled antibiotics such as azithromycin, aztreonam, and tobramycin are used as maintenance drugs.27 According to guidelines, continuous use of these antibiotics improves pulmonary function in patients with CF.28 They also reduce exacerbations in chronic infection caused by P. aeruginosa.28