SAA1 and amyloidosis: A study comparing FMF Armenian patients in 2 neighboring countries revealed that those living in Karabakh have a major deficit of SAA1 α homozygotes compared to those living in Armenia, which was believed to account for differences in amyloidosis rates (2.5% and 24%, respectively).32 Therefore, consideration the association of these genotypes is critical for the design of future genetic FMF studies.