To explore the expression level of FOXO3a along with HPV-related cervical carcinogenesis, the correlation between FOXO3a expression and the target of HPV16E6 (p53) and HPV16E7 (pRB and p107) oncoproteins was observed through GEPIA2 using TGCA (CESC Tumor/Normal) as a database. This evidence concerns the gene RBL1 and neoplasm.