For PCOS outcomes, pregnancy rate was reported in 12 studies, ovulation rate in 7 studies, resumption of menstruation in 2 studies, rate of live birth in 3 studies, abortion rate in 2 studies, serum LH in 9 studies, serum FSH in 4 studies, LH/FSH ratio in 6 studies, serum testosterone in 7 studies, endometrial thickness in 2 studies, fasting plasma glucose (FPG) in 3 studies, oral glucose tolerance test (OGTT) in 2 studies, fasting insulin in 4 studies, homeostatic model assessment for insulin resistance (HOMA-IR) in 3 studies, and BMI in 6 studies. The gene discussed is PLOD1; the disease is Insulin resistance.