SJS: Stevens-Johnson syndrome; TEN: toxic epidermal necrolysis; NSAIDs: nonsteroidal anti-inflammatory drugs; AGEP: acute generalized exanthematous pustulosis; LAD: linear IgA disease; BP: bullous pemphigoid; SDRIFE: symmetrical drug-related intertriginous and flexural exanthem; ACD: allergic contact dermatitis; TEC: toxic erythema of chemotherapy; ACE: angiotensin-converting enzyme. The gene discussed is ACE; the disease is exanthem.