NRXN1-deletion has been associated with a wide spectrum of neuropsychiatric disorders [36], such as ASD and schizophrenia [37]; dysmorphic features and ID [38]; DD, short stature, and congenital diaphragmatic hernia [39]; psychosis and enlargement of the temporal horns of the lateral ventricle [40], speech and language delay as a consistent clinical manifestation [41–44]. The gene discussed is NRXN1; the disease is congenital diaphragmatic hernia.