RNASE1 and head and neck squamous cell carcinoma: The system could protect miRNAs from RNase-A induced degradation and significantly reduce the cell viability, migration and invasion of HNSCC, providing a new idea for the application of gene co-transfection in oncotherapy.88 Besides, considering the relationship between HNSCC and various maxillofacial tissues, some hybrid cell membranes of multiple cell origins have been developed as functionalized biomimetic NPs.