We tested the serum antibodies of all participants and screened out the antibody-negative DM group (control, n=21), the anti-MDA5+DM group (MDA5+DM, n=10), the anti-TIF1-γ+DM group (TIF1-γ+DM, n=8), and the anti-Jo-1+DM group (Jo-1+DM, n=6). The gene discussed is TRIM33; the disease is dermatomyositis.