Administration of anti‐IL‐3 Rα (CD123) mAb (Talacotuzumab) also reduces the frequency of basophils in the blood174 and reports suggest that the level of production of IL‐3 from phytohemagglutinin‐stimulated peripheral blood mononuclear cells is correlated with improvement of lung function in pre‐school children with asthma.175. This evidence concerns the gene IL3 and asthma.