In DNFB‐induced AD mice, the influx of CD8+CD69+CD103+ cTRMs into the epidermis was approximately 60‐fold higher than that of controls, and these CD8+ cTRMs are essential for flare neutrophil recruitment during allergen re‐exposure, which is one of the key features of active AD.140, 141. Here, ITGAE is linked to Alzheimer disease.