The downstream related gene CXCL8 is listed as prot-b-11, with 3,394 samples and 5,270,646 SNPs; EGFR as prot-a-909, with 3,301 samples and 10,534,735 SNPs; IL6 as prot-b-2, with 3,394 samples and 5,270,646 SNPs; and the genetic information for COPD is ebi-a-GCST90018807, including 468,475 samples and 24,180,654 SNPs. Here, EGFR is linked to chronic obstructive pulmonary disease.