As DWMHs were not associated with DAT‐AC, but both DWMHs and PWMHs were correlated with the presence of hypertension and the number of microbleeds and lacunae, our findings could be interpreted as PWMH‐A being an interplay between LBD and SVCI, while DWMH may be primarily related to SVCI.40, 41. The gene discussed is SLC6A3; the disease is Hypertension.