Among them, 7 CRGs (LIAS, LIPT2, DLD, DLAT, PDHA1, CDKN2A, and GCSH) were up-regulated in NSCLC tissues, while 10 CRGs (NFE2L2, NLRP3, ATP7B, ATP7A, SLC31A1, ferredoxin 1 [FDX1], PDHB, MTF1, glutaminase [GLS], and DLST) were down-regulated (Fig. 1A). This evidence concerns the gene ATP7B and non-small cell lung carcinoma.