SOCS1 and central nervous system cancer: In the case of glioma samples obtained from the TCGA database, the biological processes most strongly linked to SOCS1 encompass innate immune responses, the positive regulation of inflammatory responses, and viral response mechanisms, with cellular components predominantly located in exosomes and intercellular spaces, and the signaling pathways mirroring those identified in the CGGA database (Fig. 3B and D).