SOCS1 and neoplasm: Then, through the Pearson algorithm, the top 203 genes most closely associated with SOCS1 from the differential expression gene sets in the CGGA and TCGA databases were selected for GO, KEGG, and GSEA enrichment analyses, indicating that SOCS1 may be involved in tumor immunity, inflammatory responses, as well as in the proliferation, differentiation, and apoptosis of T cells.