NFKB1 and neoplasm: As a regulator of the cytokine-induced NF-κB signaling pathway, which has been proven to play pivotal roles in the progression of various malignancies [51], TRAPPC9 (Trafficking Protein Particle Complex Subunit 9) over-expression could be shown to be closely related to tumor differentiation, depth of invasion, clinical stage and lymphatic metastasis in gastric cancer.