The 9q33.1 microdeletion (patient A065) causes the deletion of the TRIM32 gene and the intragenic deletion of ASTN2. Disruptions or deletions of TRIM32 are more frequent in male patients with Neurodevelopmental Disease (most common diagnoses: Autism, ADHD, speech-language delay). This evidence concerns the gene ASTN2 and Delayed speech and language development.