Mutations in PRRT2 associated with a range of neurological disorders in humans (including paraoxysmal kinesigenic dyskinia (PKD), infantile epilepsy and convulsions, hemiplagic migraines, ataxia, and intellectual disability) indicated that PRRT2 plays important roles in neurotransmission (Ebrahimi-Fakhari et al, 2015). Here, PRRT2 is linked to infantile epilepsy syndrome.