Without the current option of setting a glucose target >7.2 mmol/l, in instances of increased hypoglycaemia risk, key strategies for this AID system around PA include (1) frequent checking and monitoring of real-time CGM values and trends pre, during and post exercise; (2) having fast-acting CHO readily available to prevent or treat hypoglycaemia; and (3) aiming to limit the amount of CHO on board before PA when possible, to avoid increases in automated insulin delivery (consensus D). This evidence concerns the gene INS and Hypoglycemia.