TGF-β2 levels were significantly higher in females compared to males, both among individuals with T2D (1216 (IQR 859–1699) pg/gram wet weight plaque vs. 858 (IQR 500–1388) pg/gram wet weight plaque; p = 0.04) and without diabetes (2552 (IQR 1106–4248) pg/gram wet weight plaque vs. 1363 (IQR 839–2228) pg/gram wet weight plaque; p = 0.003). This evidence concerns the gene TGFB2 and type 2 diabetes mellitus.