DYRK1A and early-onset autosomal dominant Alzheimer disease: ↓ of kinase expression (5 μM): GSK3β, CDK5, DYRK1A, CAMK2A, MAPK1, MAPK12, MAPK14.Modulation of the hGMSC transcriptome, ↓ expression of genes involved in Alzheimer's pathogenesis.↓ expression of GSK3b and p‐GSK303B2, which plays a key role in Alzheimer's disease.