MAOB and Alzheimer disease: Chalcone (1‐phenyl‐2‐benzoylethylene) and its derivatives have been reported to have several activities, namely radical‐scavenging, metal chelation, anti‐inflammatory, AChE inhibition, neuroprotective MAO B inhibition.[214, 215] Sang et al.[216] have designed and synthesized a series of dimethylamino chalcone‐O‐alkylamine, by fusing multiple pharmacophores assessed for AD treatment.