WB analysis showed that the DNAJC7 protein was reduced by ~75% in heterozygous mutant iPSC-derived MNs (p<0.0001), consistent with previous work demonstrating a similar level of DNAJC7 reduction in ALS patients harboring 1 copy of R156X7 (Figure 2C). Here, DNAJC7 is linked to amyotrophic lateral sclerosis.