Our findings on DNAJC7 are in strong accordance with multiple studies that have demonstrated the neuronal protection qualities of other DNAJ co-chaperones in ALS, FTD, and Parkinson’s disease models, highlighting the converging importance of this class of proteins in neurodegenerative disease through their critical role in neuronal proteostasis53,56–60. Here, DNAJC7 is linked to neurodegenerative disease.