These opposite expressional changes between MiaPaCa-2and Panc-1 cells under miR-210 KO and hypoxic conditions suggestedthat miR-210 was correlated with HIF1-α, EMT, and CSC-relatedmiRs and pathways, while the downstream effects were various amongdifferent pancreatic cancer cell lines. Here, HIF1A is linked to familial pancreatic carcinoma.