Due to its upregulation under hypoxicconditions and its role in promoting tumor progression and treatmentresistance in PDAC, miR-210 can be leveraged to stratify patientsbased on their tumor’s hypoxic profile.58,59 Our data also confirm that miR-210 is upregulated by hypoxia andcorrelates with HIF1-α expression (Figure 4). This evidence concerns the gene HIF1A and neoplasm.