The biopsy revealed poorly differentiated DLBCL with tumor cells strongly positive for CD45, CD20, BCL6, MUM-1, and c-Myc (80%) (Figure 2, Figure 3, Figure 4, Figure 5, Figure 6), and negative for BCL2, cyclin D1, and CD10, representing a double-expressor type of non-germinal center DLBCL. The gene discussed is BCL2; the disease is diffuse large B-cell lymphoma.