In contrast, the responsiveness group showed lower distribution rates compared to the unresponsiveness group [115 (56.7%) vs. 84 (86.6%), respectively] regarding the positivity category of cSE (occurring at least one of the major side effects that encompasses, as predefined, SA/AV block, haemodynamic instability, alanine transaminase (ALT) to aspartate transaminase (AST), elevation, and hypo/hyperthyroidism circumstances). Here, GPT is linked to hyperthyroidism.