In order to evaluate the effect of mIL15 on the production of anti-tumor cytokines, we co-incubated UN-TIL+IL2, TIL-mIL15+IL2, and TIL-mIL15-IL2 cells with anti-CD2/CD3/CD8-conjugated T cell activation magnetic beads and measured the levels of IFN-γ and GZMB in the cell culture supernatant. The gene discussed is CD2; the disease is neoplasm.