Most identified genes in the autophagy and mitophagy signaling pathways, such as unc-51 like autophagy activating kinase 2 (ULK2), BCL2 Interacting Protein 3 (BNIP3), WD repeat domain phosphoinositide-interacting protein 1 (WIPI1) and cathepsin B (CTSB), presented significantly upregulated expression profiles following infection. The gene discussed is BNIP3; the disease is infection.