Cao et al. [21] identified risk factors for early rebleeding after EVL, including high TB, low Alb, high PT, PVT, HCC, elevated Child-Pugh scores, Child-Pugh class C, high MELD score, Japanese varicose vein class F3, EV diameter, and the number of ligature rings. This evidence concerns the gene ALB and hepatocellular carcinoma.