This study compared the expression levels of AGR3, BCHE, CBY1, CHRM3, DDHD1, DMPK, EDEM3, EDN1, HSPA2, KPNA2, LGALS3, MAOB, PIK3CA, PURA, and TMCC1 between COPD and control groups and evaluated their predictive abilities. The gene discussed is EDEM3; the disease is chronic obstructive pulmonary disease.