investigated whole blood- derived exosomes in 206 patients with various pituitary tumors (23 prolactinomas, 49 nonfunctioning pituitary adenomas, 29 somatotroph adenomas, and five corticotroph tumors) and found that exosomal lncRNA H19 expression was significantly decreased in patients with pituitary tumors compared to healthy subjects. Here, H19 is linked to pituitary gland adenoma.