There was also a reduction in the frequency of MDMs with a M1-like phenotype (CD11b+CD11c+CD86+HLA-DR+) in T2D compared to no-T2D (figure 3b), but no difference in MDMs with a M2-like phenotype (CD11b+CD11c+CD163+CD206+). This evidence concerns the gene ITGAM and type 2 diabetes mellitus.