Of note, patient 4 had subclinical ECS, which manifested after PRRT-C1 when she was admitted 15 days post treatment with hypokalaemia (potassium 2.9 mmol/L, RR 3.5–4/5 mmol/L) and hypertension due to a flare of ACTH release. The gene discussed is POMC; the disease is hypertensive disorder.