UTP20 and breast carcinoma: DRIM was first described as a molecule downregulated in metastasis in a study with submodels of a breast cancer cell line MDA MB‐435, in which the highly metastatic subline 4A4 had little or no expression of DRIM whereas the non‐metastatic subline 2C5 overexpressed DRIM (Schwirzke et al., 1998).