TGFB1 and posterior cortical atrophy: To elucidate the functional roles of NAT10 in PCa, GSEA analysis identified the potential involvement of NAT10 in nuclear translocation, RNA nuclear export, RNA metabolism, and EMT-related pathways, including stem cell pathways (Wnt and TGF-β), Extracellular Matrix (ECM) receptor pathways, and T cell receptor pathways (Fig. 3a-b).