Furthermore, we found that in the shKLF7 plus DT group (shKLF7 + DT) showed a significantly increased tumour size, volume, and weight compared to the shKLF7 group (shKLF7 + Vehicle), revealing that DT could restore the tumour suppressive effect of KLF7 knockdown on the progression of HCC (Figure 6A–C). Here, KLF7 is linked to neoplasm.