Compared to healthy controls and non‐eosinophilic (NE) CRSwNP, eosinophilic (E) CRSwNP samples showed a marked increase in HMOX1+CD163+ macrophages (Figure 6A–C), highlighting a close association between HMOX1 and CD163+ M2 macrophages. The gene discussed is HMOX1; the disease is chronic rhinosinusitis with nasal polyps.