KEGG signalling pathway analysis of the differentially expressed genes revealed enrichment of the ‘lipid and atherosclerosis’, ‘fluid sehear stress and atherosclerosis’, and ‘NF‐κB signaling pathway’ (Figure 5B), suggesting the involvement of endothelial KDM5B in the development of atherosclerosis. This evidence concerns the gene NFKB1 and atherosclerosis.