CD8+ T cells have been widely reported to be associated with a favorable prognosis in TNBC [10, 11], and NK cells are reported to be linked to a favorable prognosis in many solid tumors [36] including colorectal cancer [37], gastric cancer [38], lung cancer [39], renal cell carcinoma [40], and melanoma [41]. The gene discussed is CD8A; the disease is hereditary clear cell renal cell carcinoma.