CLCN1 and myotonic dystrophy type 1: Animal models are also useful for drug repurposing: it has been demonstrated that verapamil improves survival in a bichannelopathy mouse model which represents the combinatorial effect of Clcn1 and Cacna1s missplicing typical of DM1 patients [82], and that the administration of erythromycin improves splicing abnormalities in DM1 mice [83].