DMD is a fatal X-linked disorder caused by loss-of-function mutations in the DMD gene, leading to the absence of dystrophin and progressive degeneration of skeletal and cardiac muscle.2 Animal models have been essential for studying disease mechanisms and testing targeted therapies, such as exon skipping or gene editing to restore the DMD gene’s reading frame and dystrophin production. This evidence concerns the gene DMD and Duchenne muscular dystrophy.