The mdx mouse, which harbors a nonsense mutation in exon 23 of Dmd, or genetically engineered mouse models mimicking human DMD mutations, are widely used but have limitations for translational studies due to their small size and relatively mild phenotype.3 Consequently, several lines of dogs with spontaneous DMD mutations and genetically engineered porcine DMD models are also used.4,5. Here, DMD is linked to Duchenne muscular dystrophy.