,23 Others have shown that bacterial small RNAs from bacteria associated with bronchiolitis were more abundantly present in RSV bronchiolitis compared to rhinovirus bronchiolitis and were associated with a relative upregulation of IL-6 and IL-8 pathways and downregulation of IL-17A pathways, thus promoting proinflammatory responses.24 This evidence concerns the gene CXCL8 and bronchiolitis.