In our recent study addressing the placode lineage contribution to auditory development in mouse models for Waardenburg-Shah syndrome (Tan et al., 2023), we generated neural crest-specific (using Wnt1Cre) and placode-specific (using Pax2Cre) conditional Ednrb homozygous mutant mice (designated as Wnt1Cre/Ednrb and Pax2Cre/Ednrb respectively). This evidence concerns the gene EDNRB and Waardenburg-Shah syndrome.